Theranostics for MRI‐guided therapy: Recent developments
نویسندگان
چکیده
Recent advances in bioimaging, biochemistry, and bioinformatics have facilitated the development of personalized precision medicine. Theranostics, combining imaging modalities therapeutic agents, garnered a lot attention this context, owing to their potential monitor control treatment for individual patients. A promising strategy achieve goal involves therapy guided by magnetic resonance (MRI). MRI has high degree soft tissue contrast, low invasiveness, depth penetration good spatial resolution. MRI-guided could thus allow precise time-resolved assessment disease conditions progression. This article will give brief introduction principles MRI, describe recently developed strategies produce therapies. number theranostics based on T1, T2, or chemical exchange saturation transfer (CEST) been explored track route drug carriers vivo image diseased so as enhance bioavailability, overcome complex delivery barriers, assess responses. In addition, integration thermal offers noninvasively identify target areas, plan treatment, provide real-time efficacy tumor ablation. We also discuss intelligent nanoparticles small molecule drugs, multimodal imaging, arguing that these multifunctional agents can further improve outcomes.
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ژورنال
عنوان ژورنال: View
سال: 2021
ISSN: ['2688-3988', '2688-268X']
DOI: https://doi.org/10.1002/viw.20200134